We are pleased to share that Brian O’Neill, MD, PhD, a valued member of the Fraternal Order of Eagles Diabetes Research Center (FOEDRC), has recently been appointed to the American Society for Clinical Investigation (ASCI). This prestigious recognition is reserved for early-career physician-scientists under the age of 50 who have made significant contributions to medical research. Dr. O’Neill’s selection reflects not only his groundbreaking work in diabetes research, but also his leadership and dedication to advancing patient care. 

Dr. O’Neill’s research has focused on the often-overlooked impact of diabetes on skeletal muscle function. His investigations into how impaired insulin signaling affects muscle strength and mitochondrial energy production have provided critical insights into the accelerated muscle loss experienced by individuals with diabetes. His work has underscored the importance of glycemic control and identified potential therapeutic targets to mitigate muscle deterioration, particularly for aging patients or those recovering from major surgeries.

His appointment to the ASCI is particularly significant, as he is the first faculty member from the University of Iowa’s Department of Internal Medicine to be elected to this esteemed organization since 2017. Membership in the ASCI is highly selective, requiring nomination and endorsement from distinguished peers in the field. Dr. O’Neill’s nomination was led by his PhD mentor, Dr. E. Dale Abel, and strongly supported by leading researchers from institutions such as the National Institutes of Health and the Mayo Clinic.

As Director of the Endocrinology, Diabetes, and Metabolism Fellowship program, he plays a crucial role in shaping the next generation of physician-scientists. His recognition by the ASCI reinforces the FOEDRC’s mission to support and develop leaders in diabetes research.

Dr. O’Neill will be formally inducted into the ASCI in April 2025 in Chicago, where he will join a distinguished group of physician-scientists dedicated to advancing medical discovery. This milestone is not only a testament to his individual achievements but also reflects the collaborative and innovative environment fostered at the University of Iowa.